Entry |
|
Name |
Mutation-inactivated PRKN to Parkin-mediated ubiquitination
|
Definition |
UBCH7/8 // PRKN* // SYPH1 |
Expanded |
(7332,9246) // 5071v1 // 9627 |
Class |
|
Type |
Variant
|
Pathway |
|
Disease |
|
Gene |
7332 | UBE2L3; ubiquitin conjugating enzyme E2 L3 |
9246 | UBE2L6; ubiquitin conjugating enzyme E2 L6 |
5071 | PRKN; parkin RBR E3 ubiquitin protein ligase |
9627 | SNCAIP; synuclein alpha interacting protein |
|
Variant |
|
Reference |
|
Authors |
Chung KK, Zhang Y, Lim KL, Tanaka Y, Huang H, Gao J, Ross CA, Dawson VL, Dawson TM. |
Title |
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. |
Journal |
|
Reference |
|
Authors |
Dev KK, van der Putten H, Sommer B, Rovelli G |
Title |
Part I: parkin-associated proteins and Parkinson's disease. |
Journal |
|
LinkDB |
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