Homo sapiens (human): 7332
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Entry
7332 CDS
T01001
Symbol
UBE2L3, E2-F1, L-UBC, UBCH7, UbcM4
Name
(RefSeq) ubiquitin conjugating enzyme E2 L3
KO
K04552
ubiquitin-conjugating enzyme E2 L3 [EC:
2.3.2.23
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04120
Ubiquitin mediated proteolysis
hsa05012
Parkinson disease
hsa05022
Pathways of neurodegeneration - multiple diseases
Network
nt06420
Ubiquitin-proteasome system
nt06463
Parkinson disease
Element
N01019
Parkin-mediated ubiquitination
N01020
Mutation-inactivated PRKN to Parkin-mediated ubiquitination
N01021
Parkin-mediated ubiquitination
N01022
Mutation-inactivated PRKN to Parkin-mediated ubiquitination
N01023
Parkin-mediated ubiquitination
N01024
Mutation-inactivated PRKN to Parkin-mediated ubiquitination
N01025
Parkin-mediated ubiquitination
N01026
Mutation-inactivated PRKN to Parkin-mediated ubiquitination
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
7332 (UBE2L3)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
7332 (UBE2L3)
05022 Pathways of neurodegeneration - multiple diseases
7332 (UBE2L3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
7332 (UBE2L3)
Enzymes [BR:
hsa01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.23 E2 ubiquitin-conjugating enzyme
7332 (UBE2L3)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin-conjugating enzymes (E2)
Ubiquitin-conjugating enzymes
7332 (UBE2L3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
UQ_con
UEV
RWD
Prok-E2_B
Motif
Other DBs
NCBI-GeneID:
7332
NCBI-ProteinID:
NP_003338
OMIM:
603721
HGNC:
12488
Ensembl:
ENSG00000185651
Pharos:
P68036
(Tbio)
UniProt:
P68036
A0A024R1A4
Structure
PDB
LinkDB
All DBs
Position
22:21549447..21624034
Genome browser
AA seq
154 aa
AA seq
DB search
MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE
YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP
LRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
NT seq
465 nt
NT seq
+upstream
nt +downstream
nt
atggcggccagcaggaggctgatgaaggagcttgaagaaatccgcaaatgtgggatgaaa
aacttccgtaacatccaggttgatgaagctaatttattgacttggcaagggcttattgtt
cctgacaaccctccatatgataagggagccttcagaatcgaaatcaactttccagcagag
tacccattcaaaccaccgaagatcacatttaaaacaaagatctatcacccaaacatcgac
gaaaaggggcaggtctgtctgccagtaattagtgccgaaaactggaagccagcaaccaaa
accgaccaagtaatccagtccctcatagcactggtgaatgacccccagcctgagcacccg
cttcgggctgacctagctgaagaatactctaaggaccgtaaaaaattctgtaagaatgct
gaagagtttacaaagaaatatggggaaaagcgacctgtggactaa
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