Entry |
|
Name |
Mutation-inactivated PRKN to PINK1-Parkin-mediated MFN2 degradation
|
Definition |
PRKN* // MFN1/2 |
Expanded |
5071v1 // (55669,9927) |
Class |
|
Type |
Variant
|
Pathway |
|
Disease |
|
Gene |
5071 | PRKN; parkin RBR E3 ubiquitin protein ligase |
|
Variant |
|
Reference |
|
Authors |
Rakovic A, Grunewald A, Kottwitz J, Bruggemann N, Pramstaller PP, Lohmann K, Klein C |
Title |
Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts. |
Journal |
|
Reference |
|
Authors |
Devine MJ, Plun-Favreau H, Wood NW |
Title |
Parkinson's disease and cancer: two wars, one front. |
Journal |
|
LinkDB |
|