Entry
Name
Shigella IpgB1 to ITGA/B-FAK-RAC signaling pathway
Definition
IpgB1 -> RAC1
Expanded
K13742 -> 5879
Class
Type
Pathogen
Pathway
Disease
Gene
5879 RAC1; Rac family small GTPase 1
Perturbant
K13742 (IpgB1) ipgB1; protein IpgB1
Reference
Authors
Ohya K, Handa Y, Ogawa M, Suzuki M, Sasakawa C
Title
IpgB1 is a novel Shigella effector protein involved in bacterial invasion of host cells. Its activity to promote membrane ruffling via Rac1 and Cdc42 activation.
Journal
Reference
Authors
Huang Z, Sutton SE, Wallenfang AJ, Orchard RC, Wu X, Feng Y, Chai J, Alto NM
Title
Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics.
Journal
LinkDB
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