| Entry |
|
| Name |
Shigella IpgB2 to ITGA/B-RhoGEF-RhoA signaling pathway
|
| Definition |
IpgB2 -> RHOA |
| Expanded |
K13743 -> 387 |
| Class |
|
| Type |
Pathogen
|
| Pathway |
|
| Disease |
|
| Gene |
| 387 | RHOA; ras homolog family member A |
|
| Perturbant |
| K13743 (IpgB2) | ipgB2; protein IpgB2 |
|
| Reference |
|
| Authors |
Huang Z, Sutton SE, Wallenfang AJ, Orchard RC, Wu X, Feng Y, Chai J, Alto NM |
| Title |
Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics. |
| Journal |
|
| Reference |
|
| Authors |
Klink BU, Barden S, Heidler TV, Borchers C, Ladwein M, Stradal TE, Rottner K, Heinz DW |
| Title |
Structure of Shigella IpgB2 in complex with human RhoA: implications for the mechanism of bacterial guanine nucleotide exchange factor mimicry. |
| Journal |
|
| LinkDB |
|