Entry |
|
Name |
Shigella IpgB2 to ITGA/B-RhoGEF-RhoA signaling pathway
|
Definition |
IpgB2 -> RHOA |
Expanded |
K13743 -> 387 |
Class |
|
Type |
Pathogen
|
Pathway |
|
Disease |
|
Gene |
387 | RHOA; ras homolog family member A |
|
Perturbant |
K13743 (IpgB2) | ipgB2; protein IpgB2 |
|
Reference |
|
Authors |
Huang Z, Sutton SE, Wallenfang AJ, Orchard RC, Wu X, Feng Y, Chai J, Alto NM |
Title |
Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics. |
Journal |
|
Reference |
|
Authors |
Klink BU, Barden S, Heidler TV, Borchers C, Ladwein M, Stradal TE, Rottner K, Heinz DW |
Title |
Structure of Shigella IpgB2 in complex with human RhoA: implications for the mechanism of bacterial guanine nucleotide exchange factor mimicry. |
Journal |
|
LinkDB |
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