KEGG   NETWORK: N01095
Entry
N01095                      Network                                

Name
Escherichia Map to LPA-GNA12/13-RhoA signaling pathway
Definition
Map -> NHERF1 -> EZR -> RHOA -> ROCK1/2
  Expanded
K12787 -> 9368 -> 7430 -> 387 -> (6093,9475)
Class
nt06135 Cytoskeletal regulation (viruses and bacteria)
Type
Pathogen
Pathway
hsa05130  Pathogenic Escherichia coli infection
Disease
H00277  Enterohemorrhagic Escherichia coli (EHEC) infection
H00278  Enteropathogenic Escherichia coli (EPEC) infection
Gene
9368  SLC9A3R1; SLC9A3 regulator 1
7430  EZR; ezrin
387  RHOA; ras homolog family member A
6093  ROCK1; Rho associated coiled-coil containing protein kinase 1
9475  ROCK2; Rho associated coiled-coil containing protein kinase 2
Perturbant
K12787 (Map)  map; LEE-encoded effector Map
Reference
  Authors
Berger CN, Crepin VF, Jepson MA, Arbeloa A, Frankel G
  Title
The mechanisms used by enteropathogenic Escherichia coli to control filopodia dynamics.
  Journal
Cell Microbiol 11:309-22 (2009)
DOI:10.1111/j.1462-5822.2008.01254.x
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