| Entry |
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| Name |
Salmonella SipB to Inflammasome signaling pathway
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| Definition |
SipB -> CASP1 -> (IL1B,IL18) |
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| Expanded |
K13285 -> 834 -> (3553,3606) |
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| Class |
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| Type |
Pathogen
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| Pathway |
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| Disease |
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| Gene |
| 3553 | IL1B; interleukin 1 beta |
| 3606 | IL18; interleukin 18 |
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| Perturbant |
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| Reference |
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| Authors |
Hersh D, Monack DM, Smith MR, Ghori N, Falkow S, Zychlinsky A |
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| Title |
The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1. |
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| Journal |
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| Reference |
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| Authors |
Dreher D, Kok M, Obregon C, Kiama SG, Gehr P, Nicod LP |
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| Title |
Salmonella virulence factor SipB induces activation and release of IL-18 in human dendritic cells. |
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| Journal |
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| Reference |
|
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| Authors |
van der Velden AW, Velasquez M, Starnbach MN |
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| Title |
Salmonella rapidly kill dendritic cells via a caspase-1-dependent mechanism. |
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| Journal |
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| LinkDB |
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