KEGG   NETWORK: N01284
Entry
N01284                      Network                                

Name
Shigella IcsP to Autophagy-vesicle elongation
Definition
IcsP -| C3 -- ATG16L
  Expanded
K13520 -| 718 -- (55054,89849)
Class
nt06128 Autophagy (viruses and bacteria)
Type
Pathogen
Pathway
hsa05131  Shigellosis
Disease
H00299  Shigellosis
Gene
718  C3; complement C3
55054  ATG16L1; autophagy related 16 like 1
89849  ATG16L2; autophagy related 16 like 2
Perturbant
K13520 (IcsP)  icsP; outer membrane protease
Reference
  Authors
Sorbara MT, Foerster EG, Tsalikis J, Abdel-Nour M, Mangiapane J, Sirluck-Schroeder I, Tattoli I, van Dalen R, Isenman DE, Rohde JR, Girardin SE, Philpott DJ
  Title
Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria.
  Journal
Cell Host Microbe 23:644-652.e5 (2018)
DOI:10.1016/j.chom.2018.04.008
Reference
  Authors
King BC, Kulak K, Colineau L, Blom AM
  Title
Outside in: Roles of complement in autophagy.
  Journal
Br J Pharmacol (2020)
DOI:10.1111/bph.15192
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