| Entry |
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| Name |
AngII-AT1R-NOX2 signaling pathway
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| Definition |
AngII -> AGTR1 -> NOX2 -> ROS -> NFKB -> (VCAM1,IL6,MMP2,MMP9) |
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| Expanded |
C02135 -> 185 -> 1536 -> (C00704+C00027) -> (4790+5970) -> (7412,3569,4313,4318) |
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| Class |
nt06171 SARS coronavirus 2 (SARS-CoV-2)
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| Type |
Reference
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| Gene |
| 185 | AGTR1; angiotensin II receptor type 1 |
| 1536 | CYBB; cytochrome b-245 beta chain |
| 4790 | NFKB1; nuclear factor kappa B subunit 1 |
| 5970 | RELA; RELA proto-oncogene, NF-kB subunit |
| 7412 | VCAM1; vascular cell adhesion molecule 1 |
| 4313 | MMP2; matrix metallopeptidase 2 |
| 4318 | MMP9; matrix metallopeptidase 9 |
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| Metabolite |
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| Reference |
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| Authors |
Nguyen Dinh Cat A, Montezano AC, Burger D, Touyz RM |
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| Title |
Angiotensin II, NADPH oxidase, and redox signaling in the vasculature. |
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| Journal |
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| Reference |
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| Authors |
Forrester SJ, Booz GW, Sigmund CD, Coffman TM, Kawai T, Rizzo V, Scalia R, Eguchi S |
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| Title |
Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology. |
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| Journal |
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| Reference |
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| Authors |
Harrison DG, Cai H, Landmesser U, Griendling KK |
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| Title |
Interactions of angiotensin II with NAD(P)H oxidase, oxidant stress and cardiovascular disease. |
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| Journal |
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| LinkDB |
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