KEGG   NETWORK: N01310
Entry
N01310                      Network                                

Name
SARS-CoV-2 nsp13 to RIG-I-IRF7/3 signaling pathway
Definition
nsp13 -| TBK1
  Expanded
K25022 -| 29110
Class
nt06133 RLR signaling (viruses)
nt06171 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Type
Pathogen
Pathway
hsa05171  Coronavirus disease - COVID-19
Disease
H02398  COVID-19
Gene
29110  TBK1; TANK binding kinase 1
Perturbant
K25022 (nsp13)  nsp13; SARS coronavirus helicase
Reference
  Authors
Xia H, Cao Z, Xie X, Zhang X, Chen JY, Wang H, Menachery VD, Rajsbaum R, Shi PY
  Title
Evasion of Type I Interferon by SARS-CoV-2.
  Journal
Cell Rep 33:108234 (2020)
DOI:10.1016/j.celrep.2020.108234
Reference
  Authors
Harrison AG, Lin T, Wang P
  Title
Mechanisms of SARS-CoV-2 Transmission and Pathogenesis.
  Journal
Trends Immunol S1471-4906(20)30233-7 (2020)
DOI:10.1016/j.it.2020.10.004
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