KEGG   ORTHOLOGY: K25022
Entry
K25022                      KO                                     
Symbol
nsp13
Name
SARS coronavirus helicase [EC:5.6.2.3 3.6.4.13]
Pathway
map03230  Viral genome structure
map03240  Viral replication
map05171  Coronavirus disease - COVID-19
Network
nt06122  IFN signaling (viruses)
nt06133  RLR signaling (viruses)
nt06171  Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  Element
N01310  SARS-CoV-2 nsp13 to RIG-I-IRF7/3 signaling pathway
N01321  SARS-CoV-2 nsp1/6/13, ORF3a/6/7b and M to IFN signaling pathway
N01322  SARS-CoV-2 nsp6/13 and ORF7a/7b to IFN signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03230 Viral genome structure
    K25022  nsp13; SARS coronavirus helicase
   03240 Viral replication
    K25022  nsp13; SARS coronavirus helicase
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K25022  nsp13; SARS coronavirus helicase
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K25022  nsp13; SARS coronavirus helicase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
    3.6.4.13  RNA helicase
     K25022  nsp13; SARS coronavirus helicase
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.3  DNA 5'-3' helicase
     K25022  nsp13; SARS coronavirus helicase
Viral proteins [BR:ko03200]
 +ssRNA viruses
  Coronavirus
   K25022  nsp13; SARS coronavirus helicase
Other DBs
GO: 0003678 0003724
Genes
VP: 14254602-12(nsp13) 1489680-12(nsp13) 43740578-12(nsp13)
Reference
  Authors
Yoshimoto FK
  Title
The Proteins of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2 or n-COV19), the Cause of COVID-19.
  Journal
Protein J 39:198-216 (2020)
DOI:10.1007/s10930-020-09901-4
  Sequence
LinkDB

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