| Entry |
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| Name |
Lectin pathway of coagulation cascade, prothrombin to thrombin
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| Definition |
F2 -- ((MBL2,COLEC10/11,FCN)+MASP2) -> F2a |
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| Expanded |
2147 -- ((4153,(10584,78989),(2219,2220,8547))+10747) -> C00752 |
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| Class |
nt06171 SARS coronavirus 2 (SARS-CoV-2)
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| Type |
Reference
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| Gene |
| 2147 | F2; coagulation factor II, thrombin |
| 4153 | MBL2; mannose binding lectin 2 |
| 10584 | COLEC10; collectin subfamily member 10 |
| 78989 | COLEC11; collectin subfamily member 11 |
| 10747 | MASP2; mannan binding lectin serine peptidase 2 |
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| Metabolite |
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| Reference |
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| Authors |
Krarup A, Wallis R, Presanis JS, Gal P, Sim RB |
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| Title |
Simultaneous activation of complement and coagulation by MBL-associated serine protease 2. |
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| Journal |
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| Reference |
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| Authors |
Wiegner R, Chakraborty S, Huber-Lang M |
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| Title |
Complement-coagulation crosstalk on cellular and artificial surfaces. |
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| Journal |
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| Reference |
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| Authors |
Hess K, Ajjan R, Phoenix F, Dobo J, Gal P, Schroeder V |
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| Title |
Effects of MASP-1 of the complement system on activation of coagulation factors and plasma clot formation. |
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| Journal |
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| Reference |
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| Authors |
Gulla KC, Gupta K, Krarup A, Gal P, Schwaeble WJ, Sim RB, O'Connor CD, Hajela K |
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| Title |
Activation of mannan-binding lectin-associated serine proteases leads to generation of a fibrin clot. |
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| Journal |
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| LinkDB |
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