KEGG   NETWORK: N01318
Entry
N01318                      Network                                

Name
SARS-CoV-2 nsp1 to translation initiation
Definition
nsp1 -| 40S
  Expanded
K25011 -| (6187+6188+6189+140032+6191+6192+6193+6194+6201+6202+6203+6204+6205+6206+6207+6208+6209+6210+6217+6218+6222+6223+6224+6227+6228+6229+6230+6231+6232+6233+6234+6235+2197+3921)
Class
nt06141 Translation (viruses)
nt06171 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Type
Variant
Pathway
hsa05171  Coronavirus disease - COVID-19
Disease
H02398  COVID-19
Gene
6187  RPS2; ribosomal protein S2
6188  RPS3; ribosomal protein S3
6189  RPS3A; ribosomal protein S3A
140032  RPS4Y2; ribosomal protein S4 Y-linked 2
6191  RPS4X; ribosomal protein S4 X-linked
6192  RPS4Y1; ribosomal protein S4 Y-linked 1
6193  RPS5; ribosomal protein S5
6194  RPS6; ribosomal protein S6
6201  RPS7; ribosomal protein S7
6202  RPS8; ribosomal protein S8
6203  RPS9; ribosomal protein S9
6204  RPS10; ribosomal protein S10
6205  RPS11; ribosomal protein S11
6206  RPS12; ribosomal protein S12
6207  RPS13; ribosomal protein S13
6208  RPS14; ribosomal protein S14
6209  RPS15; ribosomal protein S15
6210  RPS15A; ribosomal protein S15a
6217  RPS16; ribosomal protein S16
6218  RPS17; ribosomal protein S17
6222  RPS18; ribosomal protein S18
6223  RPS19; ribosomal protein S19
6224  RPS20; ribosomal protein S20
6227  RPS21; ribosomal protein S21
6228  RPS23; ribosomal protein S23
6229  RPS24; ribosomal protein S24
6230  RPS25; ribosomal protein S25
6231  RPS26; ribosomal protein S26
6232  RPS27; ribosomal protein S27
6233  RPS27A; ribosomal protein S27a
6234  RPS28; ribosomal protein S28
6235  RPS29; ribosomal protein S29
2197  FAU; FAU ubiquitin like and ribosomal protein S30 fusion
3921  RPSA; ribosomal protein SA
Perturbant
K25011 (nsp1)  nsp1; SARS coronavirus host translation inhibitor nsp1
Reference
  Authors
Shi M, Wang L, Fontana P, Vora S, Zhang Y, Fu TM, Lieberman J, Wu H
  Title
SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism.
  Journal
bioRxiv 2020.09.18.302901 (2020)
DOI:10.1101/2020.09.18.302901
Reference
  Authors
Harrison AG, Lin T, Wang P
  Title
Mechanisms of SARS-CoV-2 Transmission and Pathogenesis.
  Journal
Trends Immunol S1471-4906(20)30233-7 (2020)
DOI:10.1016/j.it.2020.10.004
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