| Entry |
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| Name |
CHRNA7-E2F signaling pathway
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| Definition |
ACh -> CHRNA7 -> ARRB1 -> SRC -> RAF1 -> RB1 // E2F1 |
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| Expanded |
C01996 -> 1139 -> 408 -> 6714 -> 5894 -> 5925 // 1869 |
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| Class |
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| Type |
Reference
|
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| Gene |
| 1139 | CHRNA7; cholinergic receptor nicotinic alpha 7 subunit |
| 408 | ARRB1; arrestin beta 1 |
| 6714 | SRC; SRC proto-oncogene, non-receptor tyrosine kinase |
| 5894 | RAF1; Raf-1 proto-oncogene, serine/threonine kinase |
| 5925 | RB1; RB transcriptional corepressor 1 |
| 1869 | E2F1; E2F transcription factor 1 |
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| Metabolite |
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| Reference |
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| Authors |
Resende RR, Adhikari A |
|---|
| Title |
Cholinergic receptor pathways involved in apoptosis, cell proliferation and neuronal differentiation. |
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| Journal |
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| Reference |
|
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| Authors |
Dasgupta P, Rastogi S, Pillai S, Ordonez-Ercan D, Morris M, Haura E, Chellappan S |
|---|
| Title |
Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathways. |
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| Journal |
|
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| Reference |
|
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| Authors |
Schuller HM |
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| Title |
Is cancer triggered by altered signalling of nicotinic acetylcholine receptors? |
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| Journal |
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| LinkDB |
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