KEGG   NETWORK: N01387
Entry
N01387                      Network                                
Name
SM to DNA adducts/cross-links
Definition
SM == DNA
  Expanded
C19164 == C00039
Class
nt06250 DNA adduct formation (cancer)
Type
Env factor
Pathway
hsa05204  Chemical carcinogenesis - DNA adducts
Disease
H00014  Non-small cell lung cancer
H00013  Small cell lung cancer
Perturbant
C19164 (SM)  Sulfur mustard
Metabolite
C00039  DNA
Reference
  Authors
Matijasevic Z, Volkert MR
  Title
Base excision repair sensitizes cells to sulfur mustard and chloroethyl ethyl sulfide.
  Journal
DNA Repair (Amst) 6:733-41 (2007)
DOI:10.1016/j.dnarep.2006.12.014
Reference
  Authors
Kehe K, Szinicz L
  Title
Medical aspects of sulphur mustard poisoning.
  Journal
Toxicology 214:198-209 (2005)
DOI:10.1016/j.tox.2005.06.014
Reference
  Authors
Razavi SM, Abdollahi M, Salamati P
  Title
Cancer Events After Acute or Chronic Exposure to Sulfur Mustard: A Review of the Literature.
  Journal
Int J Prev Med 7:76 (2016)
DOI:10.4103/2008-7802.182733
Reference
  Authors
Hosseini-khalili A, Haines DD, Modirian E, Soroush M, Khateri S, Joshi R, Zendehdel K, Ghanei M, Giardina C
  Title
Mustard gas exposure and carcinogenesis of lung.
  Journal
Mutat Res 678:1-6 (2009)
DOI:10.1016/j.mrgentox.2009.05.022
Reference
  Authors
Zubel T, Burkle A, Mangerich A
  Title
Mass spectrometric analysis of sulfur mustard-induced biomolecular adducts: Are DNA adducts suitable biomarkers of exposure?
  Journal
Toxicol Lett 293:21-30 (2018)
DOI:10.1016/j.toxlet.2017.12.014
Reference
  Authors
Cheng X, Liu C, Yang Y, Liang L, Chen B, Yu H, Xia J, Liu S, Li Y
  Title
Advances in sulfur mustard-induced DNA adducts: Characterization and detection.
  Journal
Toxicol Lett 344:46-57 (2021)
DOI:10.1016/j.toxlet.2021.03.004
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