| Entry |
|
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| Name |
Ethanol to CYP-mediated metabolism
|
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| Definition |
Ethanol -- CYP2E1 -> (superoxide,OH,H2O2) |
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| Expanded |
C00469 -- 1571 -> (C00704,C16844,C00027) |
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| Class |
nt06251 CYP-mediated ROS formation (cancer)
|
|---|
| Type |
Env factor
|
|---|
| Pathway |
| hsa05208 | Chemical carcinogenesis - reactive oxygen species |
|
|---|
| Disease |
| H00048 | Hepatocellular carcinoma |
|
|---|
| Gene |
| 1571 | CYP2E1; cytochrome P450 family 2 subfamily E member 1 |
|
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| Perturbant |
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| Metabolite |
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| Reference |
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| Authors |
McKillop IH, Schrum LW |
|---|
| Title |
Role of alcohol in liver carcinogenesis. |
|---|
| Journal |
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| Reference |
|
|---|
| Authors |
Lu Y, Cederbaum AI |
|---|
| Title |
CYP2E1 and oxidative liver injury by alcohol. |
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| Journal |
|
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| Reference |
|
|---|
| Authors |
Na HK, Lee JY |
|---|
| Title |
Molecular Basis of Alcohol-Related Gastric and Colon Cancer. |
|---|
| Journal |
|
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| Reference |
|
|---|
| Authors |
Lieber CS |
|---|
| Title |
Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis. |
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| Journal |
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| LinkDB |
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