| Entry |
|
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| Name |
|
|---|
| Definition |
Tyr+BH4 -- TH -> L-Dopa -- DDC -> Dopamine -- MAO -> DOPAL |
|---|
| Expanded |
(C00082+C00272) -- 7054 -> C00355 -- 1644 -> C03758 -- (4128,4129) -> C04043 |
|---|
| Class |
|
|---|
| Type |
Reference
|
|---|
| Pathway |
|
|---|
| Gene |
| 7054 | TH; tyrosine hydroxylase |
| 1644 | DDC; dopa decarboxylase |
| 4128 | MAOA; monoamine oxidase A |
| 4129 | MAOB; monoamine oxidase B |
|
|---|
| Metabolite |
| C00355 | 3,4-Dihydroxy-L-phenylalanine |
| C04043 | 3,4-Dihydroxyphenylacetaldehyde |
|
|---|
| Reference |
|
|---|
| Authors |
Segura-Aguilar J, Paris I, Munoz P, Ferrari E, Zecca L, Zucca FA |
|---|
| Title |
Protective and toxic roles of dopamine in Parkinson's disease. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Jones DR, Moussaud S, McLean P |
|---|
| Title |
Targeting heat shock proteins to modulate alpha-synuclein toxicity. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Burbulla LF, Krainc D |
|---|
| Title |
The role of dopamine in the pathogenesis of GBA1-linked Parkinson's disease. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Segura-Aguilar J |
|---|
| Title |
On the role of endogenous neurotoxins and neuroprotection in Parkinson's disease. |
|---|
| Journal |
|
|---|
| LinkDB |
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