KEGG   NETWORK: N01620
Entry
N01620                      Network                                
Name
Blocking ubiquitination of H2AK119 by CK2
Definition
CK2 -| PRC1.3,PRC1.5 -- H2AK119+UB
  Expanded
(1457+1459+1460) -| (10336,84333+6015,6045+23429,10138+26053+64319+10238)
Class
nt06523 Epigenetic regulation by Polycomb complexes
Type
Reference
Gene
1457  CSNK2A1; casein kinase 2 alpha 1
1459  CSNK2A2; casein kinase 2 alpha 2
1460  CSNK2B; casein kinase 2 beta
10336  PCGF3; polycomb group ring finger 3
84333  PCGF5; polycomb group ring finger 5
6015  RING1; ring finger protein 1
6045  RNF2; ring finger protein 2
23429  RYBP; RING1 and YY1 binding protein
10138  YAF2; YY1 associated factor 2
26053  AUTS2; activator of transcription and developmental regulator AUTS2
64319  FBRS; fibrosin
10238  DCAF7; DDB1 and CUL4 associated factor 7
Reference
PMID:33230107
  Authors
Barbour H, Daou S, Hendzel M, Affar EB
  Title
Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes.
  Journal
Nat Commun 11:5947 (2020)
DOI:10.1038/s41467-020-19722-9
Reference
PMID:34637754
  Authors
Liu S, Aldinger KA, Cheng CV, Kiyama T, Dave M, McNamara HK, Zhao W, Stafford JM, Descostes N, Lee P, Caraffi SG, Ivanovski I, Errichiello E, Zweier C, Zuffardi O, Schneider M, Papavasiliou AS, Perry MS, Humberson J, Cho MT, Weber A, Swale A, Badea TC, Mao CA, Garavelli L, Dobyns WB, Reinberg D
  Title
NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain.
  Journal
Mol Cell 81:4663-4676.e8 (2021)
DOI:10.1016/j.molcel.2021.09.020
Reference
PMID:25519132
  Authors
Gao Z, Lee P, Stafford JM, von Schimmelmann M, Schaefer A, Reinberg D
  Title
An AUTS2-Polycomb complex activates gene expression in the CNS.
  Journal
Nature 516:349-54 (2014)
DOI:10.1038/nature13921
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