KEGG   NETWORK: N01624
Entry
N01624                      Network                                
Name
Cholesterol biosynthesis
Definition
Farnesyl-PP -- FDFT1 >> SQLE >> LSS >> CYP51A1 >> (TM7SF2,LBR) >> MSMO1 >> NSDHL >> HSD17B7 >> DHCR24 >> EBP >> SC5D -> 7-DHC -- DHCR7 -> Cholesterol
  Expanded
C00448 -- 2222 >> 6713 >> 4047 >> 1595 >> (7108,3930) >> 6307 >> 50814 >> 51478 >> 1718 >> 10682 >> 6309 -> C01164 -- 1717 -> C00187
Class
nt06034 Cholesterol biosynthesis
Type
Reference
Pathway
hsa00100  Steroid biosynthesis
Gene
2222  FDFT1; farnesyl-diphosphate farnesyltransferase 1
6713  SQLE; squalene epoxidase
4047  LSS; lanosterol synthase
1595  CYP51A1; cytochrome P450 family 51 subfamily A member 1
7108  TM7SF2; transmembrane 7 superfamily member 2
3930  LBR; lamin B receptor
6307  MSMO1; methylsterol monooxygenase 1
50814  NSDHL; NAD(P) dependent steroid dehydrogenase-like
51478  HSD17B7; hydroxysteroid 17-beta dehydrogenase 7
1718  DHCR24; 24-dehydrocholesterol reductase
10682  EBP; EBP cholestenol delta-isomerase
6309  SC5D; sterol-C5-desaturase
1717  DHCR7; 7-dehydrocholesterol reductase
Metabolite
C00448  trans,trans-Farnesyl diphosphate
C01164  7-Dehydrocholesterol
C00187  Cholesterol
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