Homo sapiens (human): 7108
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Entry
7108 CDS
T01001
Symbol
TM7SF2, ANG1, C14SR, DHCR14A, NET47
Name
(RefSeq) transmembrane 7 superfamily member 2
KO
K00222
Delta14-sterol reductase [EC:
1.3.1.70
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00100
Steroid biosynthesis
hsa01100
Metabolic pathways
Module
hsa_M00101
Cholesterol biosynthesis, FPP => cholesterol
Network
nt06034
Cholesterol biosynthesis
Element
N01624
Cholesterol biosynthesis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00100 Steroid biosynthesis
7108 (TM7SF2)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.70 Delta14-sterol reductase
7108 (TM7SF2)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
ERG4_ERG24
DUF1295
ICMT
Motif
Other DBs
NCBI-GeneID:
7108
NCBI-ProteinID:
NP_003264
OMIM:
603414
HGNC:
11863
Ensembl:
ENSG00000149809
UniProt:
O76062
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All DBs
Position
11:65111872..65116230
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AA seq
418 aa
AA seq
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MAPTQGPRAPLEFGGPLGAAALLLLLPATMFHLLLAARSGPARLLGPPASLPGLEVLWSP
RALLLWLAWLGLQAALYLLPARKVAEGQELKDKSRLRYPINGFQALVLTALLVGLGMSAG
LPLGALPEMLLPLAFVATLTAFIFSLFLYMKAQVAPVSALAPGGNSGNPIYDFFLGRELN
PRICFFDFKYFCELRPGLIGWVLINLALLMKEAELRGSPSLAMWLVNGFQLLYVGDALWH
EEAVLTTMDITHDGFGFMLAFGDMAWVPFTYSLQAQFLLHHPQPLGLPMASVICLINATG
YYIFRGANSQKNTFRKNPSDPRVAGLETISTATGRKLLVSGWWGMVRHPNYLGDLIMALA
WSLPCGVSHLLPYFYLLYFTALLVHREARDERQCLQKYGLAWQEYCRRVPYRIMPYIY
NT seq
1257 nt
NT seq
+upstream
nt +downstream
nt
atggcccccactcagggcccccgggccccgctggaattcggagggcccctgggcgccgcg
gctctgctactgctgctgcccgccaccatgttccacctgctcctggcggcccgttcgggc
cccgcgcgcctgctgggtccacccgcgtccctgccggggctggaggtgctgtggagccca
cgggcgctgctgctgtggctcgcctggctcggcctgcaggcggcgctctacctactgccg
gcgcgcaaggtggccgaggggcaggaattgaaggacaagagtcgcctgcgctatcctatt
aacggcttccaggccctggtgctgacagccctgttggtggggctggggatgtcagcgggg
ctgcctctgggggcgctcccggaaatgctcctgcccttggcgtttgtcgccaccctcacc
gctttcatcttcagcctctttctctacatgaaggcgcaggtagccccagtttcggccctg
gcacctggggggaactcaggcaatccgatttacgacttttttctgggacgagagctcaac
cctcgtatctgtttcttcgacttcaaatatttctgtgaactgcgacccggcctcatcggc
tgggtcctcatcaacctggccctgttgatgaaggaggcagagcttcgaggcagtccctca
ctggccatgtggctggtcaatggcttccagttgctctacgtgggtgatgccctctggcac
gaggaggccgtcctcaccaccatggatatcacacatgacgggtttggcttcatgctggcg
tttggggacatggcctgggtgcccttcacctacagcctgcaggcccagttcctgctgcac
cacccgcagcccctggggttgcccatggcctctgtcatctgcctcatcaatgctactggt
tactacatcttccgtggggcgaattcccagaaaaacactttccgaaagaatccttctgac
cccagagtggctgggcttgagaccatctctacagccacagggcggaaactgctggtgtct
gggtggtggggtatggtccgccatcccaactatcttggagacctcatcatggctctggct
tggtccttgccctgcggggtgtcacacctgctgccctacttctacctcctctacttcacc
gcgctgctggtgcaccgtgaggcccgggatgagcggcagtgcctgcagaagtacggcctg
gcctggcaggagtactgccggcgtgtgccttaccgcatcatgccctacatctactga
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