KEGG   NETWORK: N01625
Entry
N01625                      Network                                
Name
CYLD regulation of RIPK1/3
Definition
CYLD -> (RIPK1+RIPK3)
  Expanded
1540 -> (8737+11035)
Class
nt06527 Necroptosis
Type
Reference
Pathway
hsa04217 Necroptosis   
Gene
1540  CYLD; CYLD lysine 63 deubiquitinase
8737  RIPK1; receptor interacting serine/threonine kinase 1
11035  RIPK3; receptor interacting serine/threonine kinase 3
Reference
  Authors
Ofengeim D, Yuan J
  Title
Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death.
  Journal
Nat Rev Mol Cell Biol 14:727-36 (2013)
DOI:10.1038/nrm3683
Reference
  Authors
Lork M, Verhelst K, Beyaert R
  Title
CYLD, A20 and OTULIN deubiquitinases in NF-kappaB signaling and cell death: so similar, yet so different.
  Journal
Cell Death Differ 24:1172-1183 (2017)
DOI:10.1038/cdd.2017.46
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