Homo sapiens (human): 11035
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Entry
11035 CDS
T01001
Symbol
RIPK3, RIP3
Name
(RefSeq) receptor interacting serine/threonine kinase 3
KO
K08847
receptor-interacting serine/threonine-protein kinase 3 [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04217
Necroptosis
hsa04621
NOD-like receptor signaling pathway
hsa04623
Cytosolic DNA-sensing pathway
hsa04668
TNF signaling pathway
hsa05132
Salmonella infection
Network
nt06516
TNF signaling
nt06527
Necroptosis
Element
N01583
Regulation of extrinsic apoptotic pathway, XIAP
N01621
TNF-RIPK1/3 signaling pathway
N01625
CYLD regulation of RIPK1/3
N01631
TNFSF10-RIPK1/3 signaling pathway
N01632
FASLG-RIPK1/3 signaling pathway
N01633
TLR3-RIPK3 signaling pathway
N01634
TLR4-RIPK3 signaling pathway
N01650
SQSTM1 regulation of RIPK1/3
N01662
IFN-RIPK1/3 signaling pathway
N01663
CASP8 regulation of RIPK1/3
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
11035 (RIPK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
11035 (RIPK3)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
11035 (RIPK3)
04623 Cytosolic DNA-sensing pathway
11035 (RIPK3)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
11035 (RIPK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
11035 (RIPK3)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
11035 (RIPK3)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: TKL group
RIPK family [OT]
11035 (RIPK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RHIM
APH
Motif
Other DBs
NCBI-GeneID:
11035
NCBI-ProteinID:
NP_006862
OMIM:
605817
HGNC:
10021
Ensembl:
ENSG00000129465
UniProt:
Q9Y572
Structure
PDB
PDBj
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All DBs
Position
14:complement(24336025..24339991)
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AA seq
518 aa
AA seq
DB search
MSCVKLWPSGAPAPLVSIEELENQELVGKGGFGTVFRAQHRKWGYDVAVKIVNSKAISRE
VKAMASLDNEFVLRLEGVIEKVNWDQDPKPALVTKFMENGSLSGLLQSQCPRPWPLLCRL
LKEVVLGMFYLHDQNPVLLHRDLKPSNVLLDPELHVKLADFGLSTFQGGSQSGTGSGEPG
GTLGYLAPELFVNVNRKASTASDVYSFGILMWAVLAGREVELPTEPSLVYEAVCNRQNRP
SLAELPQAGPETPGLEGLKELMQLCWSSEPKDRPSFQECLPKTDEVFQMVENNMNAAVST
VKDFLSQLRSSNRRFSIPESGQGGTEMDGFRRTIENQHSRNDVMVSEWLNKLNLEEPPSS
VPKKCPSLTKRSRAQEEQVPQAWTAGTSSDSMAQPPQTPETSTFRNQMPSPTSTGTPSPG
PRGNQGAERQGMNWSCRTPEPNPVTGRPLVNIYNCSGVQVGDNNYLTMQQTTALPTWGLA
PSGKGRGLQHPPPVGSQEGPKDPEAWSRPQGWYNHSGK
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtgcgtcaagttatggcccagcggtgcccccgcccccttggtgtccatcgaggaa
ctggagaaccaggagctcgtcggcaaaggcgggttcggcacagtgttccgggcgcaacat
aggaagtggggctacgatgtggcggtcaagatcgtaaactcgaaggcgatatccagggag
gtcaaggccatggcaagtctggataacgaattcgtgctgcgcctagaaggggttatcgag
aaggtgaactgggaccaagatcccaagccggctctggtgactaaattcatggagaacggc
tccttgtcggggctgctgcagtcccagtgccctcggccctggccgctcctttgccgcctg
ctgaaagaagtggtgcttgggatgttttacctgcacgaccagaacccggtgctcctgcac
cgggacctcaagccatccaacgtcctgctggacccagagctgcacgtcaagctggcagat
tttggcctgtccacatttcagggaggctcacagtcagggacagggtccggggagccaggg
ggcaccctgggctacttggccccagaactgtttgttaacgtaaaccggaaggcctccaca
gccagtgacgtctacagcttcgggatcctaatgtgggcagtgcttgctggaagagaagtt
gagttgccaaccgaaccatcactcgtgtacgaagcagtgtgcaacaggcagaaccggcct
tcattggctgagctgccccaagccgggcctgagactcccggcttagaaggactgaaggag
ctaatgcagctctgctggagcagtgagcccaaggacagaccctccttccaggaatgccta
ccaaaaactgatgaagtcttccagatggtggagaacaatatgaatgctgctgtctccacg
gtaaaggatttcctgtctcagctcaggagcagcaataggagattttctatcccagagtca
ggccaaggagggacagaaatggatggctttaggagaaccatagaaaaccagcactctcgt
aatgatgtcatggtttctgagtggctaaacaaactgaatctagaggagcctcccagctct
gttcctaaaaaatgcccgagccttaccaagaggagcagggcacaagaggagcaggttcca
caagcctggacagcaggcacatcttcagattcgatggcccaacctccccagactccagag
acctcaactttcagaaaccagatgcccagccctacctcaactggaacaccaagtcctgga
ccccgagggaatcagggggctgagagacaaggcatgaactggtcctgcaggaccccggag
ccaaatccagtaacagggcgaccgctcgttaacatatacaactgctctggggtgcaagtt
ggagacaacaactacttgactatgcaacagacaactgccttgcccacatggggcttggca
ccttcgggcaaggggaggggcttgcagcaccccccaccagtaggttcgcaagaaggccct
aaagatcctgaagcctggagcaggccacagggttggtataatcatagcgggaaataa
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