KEGG   NETWORK: N01634
Entry
N01634                      Network                                
Name
TLR4-RIPK3 signaling pathway
Definition
TLR4 -> TICAM2 -> TICAM1 -> RIPK3
  Expanded
7099 -> 353376 -> 148022 -> 11035
Class
nt06527 Necroptosis
Type
Reference
Pathway
hsa04217 Necroptosis   
Gene
7099  TLR4; toll like receptor 4
353376  TICAM2; TIR domain containing adaptor molecule 2
148022  TICAM1; TIR domain containing adaptor molecule 1
11035  RIPK3; receptor interacting serine/threonine kinase 3
Reference
PMID:27368376
  Authors
Dondelinger Y, Hulpiau P, Saeys Y, Bertrand MJ, Vandenabeele P
  Title
An evolutionary perspective on the necroptotic pathway.
  Journal
Trends Cell Biol 26:721-32 (2016)
DOI:10.1016/j.tcb.2016.06.004
Reference
PMID:36040212
  Authors
Riebeling T, Kunzendorf U, Krautwald S
  Title
The role of RHIM in necroptosis.
  Journal
Biochem Soc Trans 50:1197-1205 (2022)
DOI:10.1042/BST20220535
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