NETWORK: N01650
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Entry
N01650 Network
Name
SQSTM1 regulation of RIPK1/3
Definition
SQSTM1 -> (RIPK1+RIPK3)
Expanded
8878 -> (8737+11035)
Class
nt06527
Necroptosis
Type
Reference
Pathway
hsa04217
Necroptosis
Gene
8878
SQSTM1; sequestosome 1
8737
RIPK1; receptor interacting serine/threonine kinase 1
11035
RIPK3; receptor interacting serine/threonine kinase 3
Reference
PMID:
27219062
Authors
Goodall ML, Fitzwalter BE, Zahedi S, Wu M, Rodriguez D, Mulcahy-Levy JM, Green DR, Morgan M, Cramer SD, Thorburn A
Title
The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis.
Journal
Dev Cell 37:337-49 (2016)
DOI:
10.1016/j.devcel.2016.04.018
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