| Entry |
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| Name |
Blood group H (O) antigen type 1 biosynthesis
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| Definition |
LacCer -- B3GNT5 >> B3GALT1/2/5 -> Lc4Cer -- FUT2*H -> TypeIH // ABO*O |
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| Expanded |
G00092 -- 84002 >> (8708,8707,10317) -> G00037 -- 2524v1 -> G00044 // 28v3 |
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| Class |
nt06035 Blood group carbohydrate antigen biosynthesis
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| Type |
Reference
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| Pathway |
| hsa00601 | Glycosphingolipid biosynthesis - lacto and neolacto series |
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| Gene |
| 84002 | B3GNT5; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 |
| 8708 | B3GALT1; beta-1,3-galactosyltransferase 1 |
| 8707 | B3GALT2; beta-1,3-galactosyltransferase 2 |
| 10317 | B3GALT5; beta-1,3-galactosyltransferase 5 |
| 2524 | FUT2; fucosyltransferase 2 |
| 28 | ABO; ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase |
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| Variant |
2524v1 (FUT2*H) FUT2 Se allele
28v3 (ABO*O) ABO O allele
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| Metabolite |
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| Reference |
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| Authors |
Jajosky RP, Wu SC, Zheng L, Jajosky AN, Jajosky PG, Josephson CD, Hollenhorst MA, Sackstein R, Cummings RD, Arthur CM, Stowell SR |
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| Title |
ABO blood group antigens and differential glycan expression: Perspective on the evolution of common human enzyme deficiencies. |
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| Journal |
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| LinkDB |
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