KEGG GLYCAN: G00037

GLYCAN: G00037

Entry

G00037                      Glycan

Name

Lc4Cer

Composition

(Gal)2 (Glc)1 (GlcNAc)1 (Cer)1

Mass

689.6 (Cer)

Structure

Remark

Same as:

C04910

Reaction

R06006 R06153 R06155 R06156 R06169

Pathway

map00601

Glycosphingolipid biosynthesis - lacto and neolacto series

map01100

Metabolic pathways

Module

M00070

Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer

Network

nt06035 Blood group carbohydrate antigen biosynthesis

Enzyme

2.4.1.65 2.4.1.69 2.4.1.86 2.4.1.87
2.4.3.6

Brite

Lipids [BR:br08002]
SP  Sphingolipids
  SP05 Neutral glycosphingolipids
   SP0504 Galbeta1-3GlcNAcbeta1-3Galbeta1-4Glc- (Lacto series)
    G00037  Gal-beta1->3GlcNAc-beta-1->3Gal-beta1->4Glc-beta1->1'Cer (Lc4Cer)

Reference

1 [PMID:9111138]

Authors

Henry S, Jovall PA, Ghardashkhani S, Elmgren A, Martinsson T, Larson G, Samuelsson B.

Title

Structural and immunochemical identification of Le(a), Le(b), H type 1, and related glycolipids in small intestinal mucosa of a group O Le(a-b-) nonsecretor.

Journal

Glycoconj J 14:209-23 (1997)
DOI:10.1023/a:1018541821819

Reference

2 [PMID:2960671]

Authors

Holmes EH, Hakomori S, Ostrander GK.

Title

Synthesis of type 1 and 2 lacto series glycolipid antigens in human colonic adenocarcinoma and derived cell lines is due to activation of a normally unexpressed beta 1----3N-acetylglucosaminyltransferase.

Journal

J Biol Chem 262:15649-58 (1987)

Other DBs

CCSD:

480 481 5298 5512 8599 14075 16225 16344 16405 16462 16881 17013 17704 18402 18410 18414 18428 18482 18646 19320 20843 21117 21195 23027 25474 25512 26602 27233 33733 34914 35926 36055 36111 36165 37150 37215 41524 43808 44618 47562 48134 48548 50494

GlyTouCan:

LIPIDMAPS:

JCGGDB:

LipidBank:

GlycoEpitope:

LinkDB

KCF data

NODE        5
            1   Cer        16     0
            2   Glc         7     0
            3   Gal        -1     0
            4   GlcNAc     -9     0
            5   Gal       -17     0
EDGE        4
            1     2:b1    1:1
            2     3:b1    2:4
            3     4:b1    3:3
            4     5:b1    4:3

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