Entry |
|
Name |
CXCR4-GNA12/13 signaling pathway
|
Definition |
CXCL12 -> CXCR4 -> GNA12/13 -> (ARHGEF12,ARHGEF1) |
Expanded |
6387 -> 7852 -> (2768,10672) -> (23365,9138) |
Class |
|
Type |
Reference
|
Pathway |
hsa04810 | Regulation of actin cytoskeleton |
|
Gene |
6387 | CXCL12; C-X-C motif chemokine ligand 12 |
7852 | CXCR4; C-X-C motif chemokine receptor 4 |
2768 | GNA12; G protein subunit alpha 12 |
10672 | GNA13; G protein subunit alpha 13 |
23365 | ARHGEF12; Rho guanine nucleotide exchange factor 12 |
9138 | ARHGEF1; Rho guanine nucleotide exchange factor 1 |
|
Reference |
|
Authors |
Juneja J, Casey PJ |
Title |
Role of G12 proteins in oncogenesis and metastasis. |
Journal |
|
Reference |
|
Authors |
Tan W, Martin D, Gutkind JS |
Title |
The Galpha13-Rho signaling axis is required for SDF-1-induced migration through CXCR4. |
Journal |
|
LinkDB |
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