 | | NETWORK: N01774 | |
| Entry |
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| Name |
ERK-DUSP4 negative feedback pathway
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| Definition |
SAM -- DNMT3A -| DUSP4 -| ERK |
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| Expanded |
C00019 -- 1788 -| 1846 -| (5594,5595) |
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| Class |
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| Type |
Reference
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| Pathway |
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| Gene |
| 1788 | DNMT3A; DNA methyltransferase 3 alpha |
| 1846 | DUSP4; dual specificity phosphatase 4 |
| 5594 | MAPK1; mitogen-activated protein kinase 1 |
| 5595 | MAPK3; mitogen-activated protein kinase 3 |
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| Metabolite |
| C00019 | S-Adenosyl-L-methionine |
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| Reference |
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| Authors |
Ampomah PB, Cai B, Sukka SR, Gerlach BD, Yurdagul A Jr, Wang X, Kuriakose G, Darville LNF, Sun Y, Sidoli S, Koomen JM, Tall AR, Tabas I |
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| Title |
Macrophages use apoptotic cell-derived methionine and DNMT3A during efferocytosis to promote tissue resolution. |
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| Journal |
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| Reference |
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| Authors |
Kalinkova L, Sevcikova A, Stevurkova V, Fridrichova I, Ciernikova S |
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| Title |
Targeting DNA Methylation in Leukemia, Myelodysplastic Syndrome, and Lymphoma: A Potential Diagnostic, Prognostic, and Therapeutic Tool. |
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| Journal |
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| LinkDB |
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