| Entry |
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|---|
| Name |
Dopamine metabolism in astrocyte
|
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| Definition |
Dopamine -- (COMT,LRTOMT) >> MAO >> ADH -> HVA |
|---|
| Expanded |
C03758 -- (1312,220074) >> (4128,4129) >> (218,221,222) -> C05582 |
|---|
| Class |
nt06544 Neuroactive ligand signaling
|
|---|
| Type |
Reference
|
|---|
| Pathway |
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|---|
| Gene |
| 1312 | COMT; catechol-O-methyltransferase |
| 220074 | LRTOMT; leucine rich transmembrane and O-methyltransferase domain containing |
| 4128 | MAOA; monoamine oxidase A |
| 4129 | MAOB; monoamine oxidase B |
| 218 | ALDH3A1; aldehyde dehydrogenase 3 family member A1 |
| 221 | ALDH3B1; aldehyde dehydrogenase 3 family member B1 |
| 222 | ALDH3B2; aldehyde dehydrogenase 3 family member B2 |
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|---|
| Metabolite |
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| Reference |
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|---|
| Authors |
Nimgampalle M, Chakravarthy H, Sharma S, Shree S, Bhat AR, Pradeepkiran JA, Devanathan V |
|---|
| Title |
Neurotransmitter systems in the etiology of major neurological disorders: Emerging insights and therapeutic implications. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Xu H, Yang F |
|---|
| Title |
The interplay of dopamine metabolism abnormalities and mitochondrial defects in the pathogenesis of schizophrenia. |
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| Journal |
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| LinkDB |
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