KEGG   NETWORK: N01935
Entry
N01935                      Network                                
Name
NFASC interactions
Definition
(GLDN,NRCAM,(CNTN1+CNTNAP1)) == NFASC -> (ANK2/3+SPTAN1+SPTBN),(EZR+ACTB,ACTG1),SCN8A
  Expanded
(342035,4897,(1272+8506)) == 23114 -> (287,288+6709+6711,6712,57731,51332),(7430+60,71),6334
Class
nt06546 IgSF CAM signaling
Type
Reference
Pathway
hsa04517 IGSF CAM signaling   
Gene
342035  GLDN; gliomedin
4897  NRCAM; neuronal cell adhesion molecule
1272  CNTN1; contactin 1
8506  CNTNAP1; contactin associated protein 1
23114  NFASC; neurofascin
287  ANK2; ankyrin 2
288  ANK3; ankyrin 3
6709  SPTAN1; spectrin alpha, non-erythrocytic 1
6711  SPTBN1; spectrin beta, non-erythrocytic 1
6712  SPTBN2; spectrin beta, non-erythrocytic 2
57731  SPTBN4; spectrin beta, non-erythrocytic 4
51332  SPTBN5; spectrin beta, non-erythrocytic 5
7430  EZR; ezrin
60  ACTB; actin beta
71  ACTG1; actin gamma 1
6334  SCN8A; sodium voltage-gated channel alpha subunit 8
Reference
  Authors
Kalafatakis I, Savvaki M, Velona T, Karagogeos D
  Title
Implication of Contactins in Demyelinating Pathologies.
  Journal
Life (Basel) 11:life11010051 (2021)
DOI:10.3390/life11010051
Reference
  Authors
Gao Y, Kong L, Liu S, Liu K, Zhu J
  Title
Impact of Neurofascin on Chronic Inflammatory Demyelinating Polyneuropathy via Changing the Node of Ranvier Function: A Review.
  Journal
Front Mol Neurosci 14:779385 (2021)
DOI:10.3389/fnmol.2021.779385
Reference
  Authors
Gennarini G, Bizzoca A, Picocci S, Puzzo D, Corsi P, Furley AJW
  Title
The role of Gpi-anchored axonal glycoproteins in neural development and neurological disorders.
  Journal
Mol Cell Neurosci 81:49-63 (2017)
DOI:10.1016/j.mcn.2016.11.006
Reference
  Authors
Leshchyns'ka I, Sytnyk V
  Title
Reciprocal Interactions between Cell Adhesion Molecules of the Immunoglobulin Superfamily and the Cytoskeleton in Neurons.
  Journal
Front Cell Dev Biol 4:9 (2016)
DOI:10.3389/fcell.2016.00009
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