KEGG   NETWORK: N01937
Entry
N01937                      Network                                
Name
CNTN2 interactions
Definition
(CNTN2,L1CAM,NRCAM,NCAM,APP,PTPRZ1) == CNTN2+CNTNAP2 -> (EPB41L3+SPTAN1+SPTBN2),KCNA1/2/4/6
  Expanded
(6900,3897,4897,4684,4685,351,5803) == (6900+26047) -> (23136+6709+6712),(3736,3737,3739,3742)
Class
nt06546 IgSF CAM signaling
Type
Reference
Pathway
hsa04517 IGSF CAM signaling   
Gene
6900  CNTN2; contactin 2
3897  L1CAM; L1 cell adhesion molecule
4897  NRCAM; neuronal cell adhesion molecule
4684  NCAM1; neural cell adhesion molecule 1
4685  NCAM2; neural cell adhesion molecule 2
351  APP; amyloid beta precursor protein
5803  PTPRZ1; protein tyrosine phosphatase receptor type Z1
26047  CNTNAP2; contactin associated protein 2
23136  EPB41L3; erythrocyte membrane protein band 4.1 like 3
6709  SPTAN1; spectrin alpha, non-erythrocytic 1
6712  SPTBN2; spectrin beta, non-erythrocytic 2
3736  KCNA1; potassium voltage-gated channel subfamily A member 1
3737  KCNA2; potassium voltage-gated channel subfamily A member 2
3739  KCNA4; potassium voltage-gated channel subfamily A member 4
3742  KCNA6; potassium voltage-gated channel subfamily A member 6
Reference
PMID:33451101
  Authors
Kalafatakis I, Savvaki M, Velona T, Karagogeos D
  Title
Implication of Contactins in Demyelinating Pathologies.
  Journal
Life (Basel) 11:life11010051 (2021)
DOI:10.3390/life11010051
Reference
PMID:34975399
  Authors
Gao Y, Kong L, Liu S, Liu K, Zhu J
  Title
Impact of Neurofascin on Chronic Inflammatory Demyelinating Polyneuropathy via Changing the Node of Ranvier Function: A Review.
  Journal
Front Mol Neurosci 14:779385 (2021)
DOI:10.3389/fnmol.2021.779385
Reference
PMID:19703450
  Authors
Labasque M, Faivre-Sarrailh C
  Title
GPI-anchored proteins at the node of Ranvier.
  Journal
FEBS Lett 584:1787-92 (2010)
DOI:10.1016/j.febslet.2009.08.025
Reference
PMID:27871938
  Authors
Gennarini G, Bizzoca A, Picocci S, Puzzo D, Corsi P, Furley AJW
  Title
The role of Gpi-anchored axonal glycoproteins in neural development and neurological disorders.
  Journal
Mol Cell Neurosci 81:49-63 (2017)
DOI:10.1016/j.mcn.2016.11.006
Reference
PMID:36982638
  Authors
Komatsuya K, Kikuchi N, Hirabayashi T, Kasahara K
  Title
The Regulatory Roles of Cerebellar Glycosphingolipid Microdomains/Lipid Rafts.
  Journal
Int J Mol Sci 24:ijms24065566 (2023)
DOI:10.3390/ijms24065566
Reference
PMID:30530999
  Authors
Chatterjee M, Schild D, Teunissen CE
  Title
Contactins in the central nervous system: role in health and disease.
  Journal
Neural Regen Res 14:206-216 (2019)
DOI:10.4103/1673-5374.244776
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