KEGG   REACTION: R00235
Entry
R00235                      Reaction                               
Name
acetate:CoA ligase (AMP-forming)
Definition
ATP + Acetate + CoA <=> AMP + Diphosphate + Acetyl-CoA
Equation
C00002 + C00033 + C00010 <=> C00020 + C00013 + C00024
Comment
two-step reaction (see R00316+R00236)
Reaction class
RC00004  C00010_C00024
RC00012  C00024_C00033
Enzyme
6.2.1.1
Pathway
rn00010  Glycolysis / Gluconeogenesis
rn00630  Glyoxylate and dicarboxylate metabolism
rn00680  Methane metabolism
rn00720  Other carbon fixation pathways
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Module
M00357  Methanogenesis, acetate => methane
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.1
     R00235  ATP + Acetate + CoA <=> AMP + Diphosphate + Acetyl-CoA
Orthology
K01895  acetyl-CoA synthetase [EC:6.2.1.1]
K01913  acetate/butyrate---CoA ligase [EC:6.2.1.1 6.2.1.2]
Other DBs
RHEA: 23179
LinkDB

KEGG   REACTION: R00316
Entry
R00316                      Reaction                               
Name
ATP:acetate adenylyltransferase
Definition
ATP + Acetate <=> Diphosphate + Acetyl adenylate
Equation
C00002 + C00033 <=> C00013 + C05993
Comment
the first step of two-step reaction (see R00235, R00316+R00236)
subsequently R00236
Reaction class
RC00043  C00033_C05993
Enzyme
6.2.1.1
Pathway
rn00620  Pyruvate metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.1
     R00316  ATP + Acetate <=> Diphosphate + Acetyl adenylate
Orthology
K01895  acetyl-CoA synthetase [EC:6.2.1.1]
K01913  acetate/butyrate---CoA ligase [EC:6.2.1.1 6.2.1.2]
LinkDB

KEGG   REACTION: R00236
Entry
R00236                      Reaction                               
Name
acetyl adenylate:CoA acetyltransferase
Definition
Acetyl adenylate + CoA <=> AMP + Acetyl-CoA
Equation
C05993 + C00010 <=> C00020 + C00024
Comment
the second step of two-step reaction (see R00235, R00316+R00236)
following after R00316
Reaction class
RC00004  C00010_C00024
RC00070  C00020_C05993
RC02746  C00024_C05993
Enzyme
6.2.1.1
Pathway
rn00620  Pyruvate metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.1
     R00236  Acetyl adenylate + CoA <=> AMP + Acetyl-CoA
Orthology
K01895  acetyl-CoA synthetase [EC:6.2.1.1]
K01913  acetate/butyrate---CoA ligase [EC:6.2.1.1 6.2.1.2]
LinkDB

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