KEGG   REACTION: R00286
Entry
R00286                      Reaction                               
Name
UDP-glucose:NAD+ 6-oxidoreductase
Definition
UDP-glucose + H2O + 2 NAD+ <=> UDP-glucuronate + 2 NADH + 2 H+
Equation
C00029 + C00001 + 2 C00003 <=> C00167 + 2 C00004 + 2 C00080
Reaction class
RC00001  C00003_C00004
RC00291  C00029_C00167
Enzyme
1.1.1.22
Pathway
rn00040  Pentose and glucuronate interconversions
rn00053  Ascorbate and aldarate metabolism
rn00520  Amino sugar and nucleotide sugar metabolism
rn00541  O-Antigen nucleotide sugar biosynthesis
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
rn01250  Biosynthesis of nucleotide sugars
Module
M00014  Glucuronate pathway (uronate pathway)
M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.22
     R00286  UDP-glucose + H2O + 2 NAD+ <=> UDP-glucuronate + 2 NADH + 2 H+
Orthology
K00012  UDPglucose 6-dehydrogenase [EC:1.1.1.22]
Other DBs
RHEA: 23599
LinkDB

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