KEGG   REACTION: R00424
Entry
R00424                      Reaction                               
Name
GTP 7,8-8,9-dihydrolase
Definition
GTP + H2O <=> 7,8-Dihydroneopterin 3'-triphosphate + Formate
Equation
C00044 + C00001 <=> C04895 + C00058
Comment
four-step reaction (see R00428+R05046+R05048+R04639)
Reaction class
RC00292  C00044_C04895
RC02504  C00044_C00058
Enzyme
3.5.4.16
Pathway
rn01240  Biosynthesis of cofactors
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.16
     R00424  GTP + H2O <=> 7,8-Dihydroneopterin 3'-triphosphate + Formate
Orthology
K01495  GTP cyclohydrolase IA [EC:3.5.4.16]
K09007  GTP cyclohydrolase IB [EC:3.5.4.16]
K22391  GTP cyclohydrolase I [EC:3.5.4.16]
Other DBs
RHEA: 17476
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