KEGG REACTION: R01227

REACTION: R01227

Entry

R01227                      Reaction

Name

guanosine 5'-monophosphate phosphohydrolase

Definition

GMP + H2O <=> Guanosine + Orthophosphate

Equation

C00144 + C00001 <=> C00387 + C00009

Reaction class

RC00017

C00144_C00387

Enzyme

3.1.3.5 3.1.3.-

Pathway

rn00230

Purine metabolism

rn01100

Metabolic pathways

rn01232

Nucleotide metabolism

Module

M00959

Guanine ribonucleotide degradation, GMP => Urate

Brite

Enzymatic reactions [BR:br08201]
3. Hydrolase reactions
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.5
     R01227  GMP + H2O <=> Guanosine + Orthophosphate
    3.1.3.-
     R01227  GMP + H2O <=> Guanosine + Orthophosphate
IUBMB reaction hierarchy [BR:br08202]
3. Hydrolase reactions
  3.1.3.5
   R07297  5'-Ribonucleotide <=> Ribonucleoside
    R01227  GMP <=> Guanosine

Orthology

K01081

5'-nucleotidase [EC:3.1.3.5]

K02566

5'-nucleotidase [EC:3.1.3.5]

K03787

5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]

K08693

2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase / 5'-nucleotidase [EC:3.1.4.16 3.1.3.6 3.1.3.5]

K11751

5'-nucleotidase / UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45]

K19970