| Entry |
|
| Symbol |
E3.1.3.5
|
| Name |
|
| Pathway |
| map00760 | Nicotinate and nicotinamide metabolism |
| map01110 | Biosynthesis of secondary metabolites |
|
| Module |
| M00958 | Adenine ribonucleotide degradation, AMP => Urate |
| M00959 | Guanine ribonucleotide degradation, GMP => Urate |
|
| Reaction |
| R00183 | adenosine 5'-monophosphate phosphohydrolase |
| R00511 | cytidine-5'-monophosphate phosphohydrolase |
| R00963 | uridine 5'-monophosphate phosphohydrolase |
| R01126 | inosine 5'-monophosphate phosphohydrolase |
| R01227 | guanosine 5'-monophosphate phosphohydrolase |
| R01569 | thymidylate 5'-phosphohydrolase |
| R01664 | 2'-deoxycytidine 5'-monophosphate phosphohydrolase |
| R01968 | 2'-deoxyguanosine 5'-monophosphate phosphohydrolase |
| R02088 | 2'-deoxyadenosine 5'-monophosphate phosphohydrolase |
| R02102 | 2'-deoxyuridine 5'-monophosphate phosphohydrolase |
| R02323 | nicotinamide ribonucleotide phosphohydrolase |
| R02719 | xanthosine 5'-phosphate phosphohydrolase |
| R03346 | nicotinate D-ribonucleotide phosphohydrolase |
|
| Disease |
| H00266 | Hereditary spastic paraplegia |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
K01081 E3.1.3.5; 5'-nucleotidase
00240 Pyrimidine metabolism
K01081 E3.1.3.5; 5'-nucleotidase
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
K01081 E3.1.3.5; 5'-nucleotidase
Enzymes [BR:ko01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.5 5'-nucleotidase
K01081 E3.1.3.5; 5'-nucleotidase
|
| Other DBs |
|
| Genes |
» show all
|
| Reference |
|
| Authors |
Hunsucker SA, Spychala J, Mitchell BS |
| Title |
Human cytosolic 5'-nucleotidase I: characterization and role in nucleoside analog resistance. |
| Journal |
|
| Sequence |
|
| Reference |
|
| Authors |
Sala-Newby GB, Newby AC |
| Title |
Cloning of a mouse cytosolic 5'-nucleotidase-I identifies a new gene related to human autoimmune infertility-related protein. |
| Journal |
|
| Sequence |
|
| Reference |
|
| Authors |
Oka J, Matsumoto A, Hosokawa Y, Inoue S |
| Title |
Molecular cloning of human cytosolic purine 5'-nucleotidase. |
| Journal |
|
| Sequence |
|
| LinkDB |
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