KEGG   REACTION: R01565
Entry
R01565                      Reaction                               
Name
N,N-dimethylglycine,5,6,7,8-tetrahydrofolate:electron-transferflavoprotein oxidoreductase (demethylating,5,10-methylenetetrahydrofolate-forming)
Definition
N,N-Dimethylglycine + Tetrahydrofolate + Electron-transferring flavoprotein <=> Sarcosine + 5,10-Methylenetetrahydrofolate + Reduced electron-transferring flavoprotein
Equation
C01026 + C00101 + C04253 <=> C00213 + C00143 + C04570
Reaction class
RC00181  C00213_C01026
Enzyme
1.5.8.4
Pathway
rn00260  Glycine, serine and threonine metabolism
rn00670  One carbon pool by folate
rn01100  Metabolic pathways
Module
M00974  Betaine metabolism, animals, betaine => glycine
M00975  Betaine degradation, bacteria, betaine => pyruvate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.5  Acting on the CH-NH group of donors
   1.5.8  With a flavin or flavoprotein as acceptor
    1.5.8.4
     R01565  N,N-Dimethylglycine + Tetrahydrofolate + Electron-transferring flavoprotein <=> Sarcosine + 5,10-Methylenetetrahydrofolate + Reduced electron-transferring flavoprotein
Orthology
K00315  dimethylglycine dehydrogenase [EC:1.5.8.4]
Other DBs
RHEA: 52859
LinkDB

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