KEGG   REACTION: R01616
Entry
R01616                      Reaction                               
Name
4-coumarate:CoA ligase (AMP-forming)
Definition
ATP + 4-Coumarate + CoA <=> AMP + Diphosphate + p-Coumaroyl-CoA
Equation
Reaction class
RC00004  C00010_C00223
RC00131  C00223_C00811
Enzyme
Pathway
rn00130  Ubiquinone and other terpenoid-quinone biosynthesis
rn00940  Phenylpropanoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00039  Monolignol biosynthesis, phenylalanine/tyrosine => monolignol
M00137  Flavanone biosynthesis, phenylalanine => naringenin
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.12
     R01616  ATP + 4-Coumarate + CoA <=> AMP + Diphosphate + p-Coumaroyl-CoA
Orthology
K01904  4-coumarate--CoA ligase [EC:6.2.1.12]
Reference
1  [PMID:12232327]
  Authors
Loscher R, Heide L
  Title
Biosynthesis of p-Hydroxybenzoate from p-Coumarate and p-Coumaroyl-Coenzyme A in Cell-Free Extracts of Lithospermum erythrorhizon Cell Cultures.
  Journal
Plant Physiol 106:271-279 (1994)
DOI:10.1104/pp.106.1.271
Reference
2  [PMID:11583838]
  Authors
Meganathan R
  Title
Ubiquinone biosynthesis in microorganisms.
  Journal
FEMS Microbiol Lett 203:131-9 (2001)
DOI:10.1111/j.1574-6968.2001.tb10831.x
Other DBs
RHEA: 19644
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