KEGG   ORTHOLOGY: K01904
Entry
K01904                      KO                                     
Symbol
4CL
Name
4-coumarate--CoA ligase [EC:6.2.1.12]
Pathway
map00130  Ubiquinone and other terpenoid-quinone biosynthesis
map00940  Phenylpropanoid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00039  Monolignol biosynthesis, phenylalanine/tyrosine => monolignol
M00137  Flavanone biosynthesis, phenylalanine => naringenin
Reaction
R01616  4-coumarate:CoA ligase (AMP-forming)
R01943  caffeate:CoA ligase (AMP-forming)
R02194  ferulate:CoA ligase (AMP-forming)
R02221  sinapate:CoA ligase (AMP-forming)
R02255  trans-cinnamate:CoA ligase (AMP-forming)
R06583  4-coumarate:CoA ligase (AMP-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00130 Ubiquinone and other terpenoid-quinone biosynthesis
    K01904  4CL; 4-coumarate--CoA ligase
  09110 Biosynthesis of other secondary metabolites
   00940 Phenylpropanoid biosynthesis
    K01904  4CL; 4-coumarate--CoA ligase
Enzymes [BR:ko01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.12  4-coumarate---CoA ligase
     K01904  4CL; 4-coumarate--CoA ligase
Other DBs
GO: 0016207
Genes
BFO: 118414737 118414744 118421842 118422502 118422909 118423020
BBEL: 109470465 109471068 109471070 109483777 109488242
CIN: 100175890 100175931 100178317 100179929 100180897 100181730 100182943 100187395 113473993
SCLV: 120326340 120329405 120329694 120331059 120332422 120332870 120333042 120333228 120333252 120336715 120337870 120341793 120341961 120341982 120341999 120342017 120342497 120343057 120344684 120345049 120345187 120346001 120346126 120346127 120346485 120346487 120346636
SPU: 581946
LPIC: 129279779
APLC: 110978158
AFIL: 140165858 140166658 140171536
AJC: 117112444
SKO: 100373806 100374282 100377026 100377139 100377142 102807583
DME: Dmel_CG9009(pdgy)
DSE: 6619579
DSI: Dsimw501_GD15826(Dsim_GD15826) Dsimw501_GD21070(Dsim_GD21070) Dsimw501_GD25844(Dsim_GD25844) Dsimw501_GD25845(Dsim_GD25845)
DAN: 6502179
DVI: 6633750(pdgy) 6635150
TDA: 119669756
GFS: 119635065
CLON: 129608084
HIS: 119654451
CNS: 116350551
CGIG: 122399689
CGLO: 123263351
CINS: 118071630
VCAN: 122418447
SOY: 115890963
DCOR: 135792765
APLN: 108743060
CCRC: 123697206
LSIN: 126966676
CFEL: 113384816
ACOO: 126846937
DVT: 126909526
PMOO: 119589523
PPOI: 119103126
VDE: 111247541
VJA: 111267097
CEL: CELE_ZK1127.2(acs-6)
CBR: CBG_19807
BMY: BM_BM3569(Bma-acs-12)
CANU: 128156557
OED: 125650259
MCAF: 127737346
OBI: 106877149
OSN: 115217415
AQU: 100635352
OSA: 112935996 4328485(4CL-3) 4330407(4CL.2) 4331650(4CLL1) 4341718(4CL4) 4342925(4CLL7) 4345054(4CL) 4345717(4CL5) 9267647 9269113 9270232(4CLL5) 9272068
YLI: 2906493(YALI2_A00487g) 2906601(YALI2_A00238g) 2908078(YALI2_F00853g) 2911232(YALI2_D00352g) 2911816(YALI2_E00412g) 2912806(YALI2_E00242g) 2912831(YALI2_E01510g)
SLB: AWJ20_3904(PCS60)
NCR: NCU10546
NTE: NEUTE1DRAFT97785(NEUTE1DRAFT_97785)
SMP: 10803361(SMAC4_06545) 10805262(SMAC4_09294)
RTHE: 98128777(VTJ83DRAFT_7323)
PGRI: PgNI_11474
MAW: 19246701(J3458_012864) 19251698(J3458_008747)
MBRN: 26241205(azaF_1)
PLJ: 28883501(PLICBS_000536) 28888147(PLICBS_003356) 28890544(PLICBS_005093)
CDET: 87949350(CDEST_12850) 87950190(CDEST_13690)
CPW: 9691948(D8B26_005441) 9694311(D8B26_002916) 9694441(D8B26_002758) 9695537(D8B26_005986) 9696374(D8B26_000990) 9697708(D8B26_007354)
PBL: PAAG_05989 PAAG_08670 PAAG_12136(PAAG_06016)
PTRR: 6339933(PtrM4_025390) 6347026(PtrM4_031980) 6347041(PtrM4_032140) 6348144(PtrM4_085860) 6348585(PtrM4_076140)
ADAC: 96082542(ACET3X_002220) 96082711(ACET3X_002389) 96087962(ACET3X_007640) 96088449(ACET3X_008127) 96088470(ACET3X_008148) 96089766(ACET3X_009444)
ABP: AGABI1DRAFT119847(AGABI1DRAFT_119847) AGABI1DRAFT131074(AGABI1DRAFT_131074) AGABI1DRAFT40522(AGABI1DRAFT_40522) AGABI1DRAFT97118(AGABI1DRAFT_97118)
ABV: AGABI2DRAFT212169(AGABI2DRAFT_212169) AGABI2DRAFT239433(AGABI2DRAFT_239433) AGABI2DRAFT239435(AGABI2DRAFT_239435) AGABI2DRAFT72962(AGABI2DRAFT_72962)
SCM: SCHCO_02604831(SCHCODRAFT_02604831) SCHCO_02615598(SCHCODRAFT_02615598)
MRT: MRET_0077
DDI: DDB_G0284743(4cl3) DDB_G0284745(4cl2) DDB_G0284831(4cl1)
DFA: DFA_09884(4cl1)
SPAR: SPRG_06390
 » show all
Reference
  Authors
Ehlting J, Buttner D, Wang Q, Douglas CJ, Somssich IE, Kombrink E
  Title
Three 4-coumarate:coenzyme A ligases in Arabidopsis thaliana represent two evolutionarily divergent classes in angiosperms.
  Journal
Plant J 19:9-20 (1999)
DOI:10.1046/j.1365-313x.1999.00491.x
  Sequence
Reference
  Authors
Schneider K, Kienow L, Schmelzer E, Colby T, Bartsch M, Miersch O, Wasternack C, Kombrink E, Stuible HP
  Title
A new type of peroxisomal acyl-coenzyme A synthetase from Arabidopsis thaliana has the catalytic capacity to activate biosynthetic precursors of jasmonic acid.
  Journal
J Biol Chem 280:13962-72 (2005)
DOI:10.1074/jbc.M413578200
  Sequence
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