KEGG   REACTION: R01676
Entry
R01676                      Reaction                               
Name
guanine aminohydrolase
Definition
Guanine + H2O <=> Xanthine + Ammonia
Equation
C00242 + C00001 <=> C00385 + C00014
Reaction class
RC00204  C00242_C00385
Enzyme
3.5.4.3
Pathway
rn00230  Purine metabolism
rn01100  Metabolic pathways
rn01232  Nucleotide metabolism
Module
M00959  Guanine ribonucleotide degradation, GMP => Urate
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.3
     R01676  Guanine + H2O <=> Xanthine + Ammonia
Orthology
K01487  guanine deaminase [EC:3.5.4.3]
Other DBs
RHEA: 14668
LinkDB

KEGG   RCLASS: RC00204
Entry
RC00204                     RClass                                 
Definition
C8y-C8y:N1a+*-*+O5x:N4x+N5x-N4x+N4x
N5x-N4x:*-*:C8y+C8y-C8y+C8y
Reactant pair
C00144_C00655    C00242_C00385    C00366_C20155
C00387_C01762    C00835_C02333    C01268_C01304
C04454_C18910    C16618_C16619
Related class
Reaction
R01230 R01231 R01676 R02145 R02974 R03459 R08244 R09377
R09876
Enzyme
3.5.4.3         3.5.4.15        3.5.4.24        3.5.4.26        
3.5.4.32        6.3.5.2
Pathway
rn00230  Purine metabolism
rn00740  Riboflavin metabolism
rn00983  Drug metabolism - other enzymes
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01232  Nucleotide metabolism
rn01240  Biosynthesis of cofactors
Orthology
K01487  guanine deaminase [EC:3.5.4.3]
K01498  diaminohydroxyphosphoribosylaminopyrimidine deaminase [EC:3.5.4.26]
K01951  GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
K11752  diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
K14655  tRNA pseudouridine32 synthase / 2,5-diamino-6-(5-phospho-D-ribitylamino)-pyrimidin-4(3H)-one deaminase [EC:5.4.99.28]

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