Entry |
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Symbol |
guaA, GMPS
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Name |
GMP synthase (glutamine-hydrolysing) [EC: 6.3.5.2]
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Pathway |
map00983 | Drug metabolism - other enzymes |
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Module |
M00050 | Guanine ribonucleotide biosynthesis, IMP => GDP,GTP |
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Reaction |
R01230 | xanthosine-5'-phosphate:ammonia ligase (AMP-forming) |
R01231 | xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming) |
R08244 | 6-thioxanthine 5'-monophosphate:L-glutamine amido-ligase (AMP-forming) |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
K01951 guaA, GMPS; GMP synthase (glutamine-hydrolysing)
09111 Xenobiotics biodegradation and metabolism
00983 Drug metabolism - other enzymes
K01951 guaA, GMPS; GMP synthase (glutamine-hydrolysing)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors
K01951 guaA, GMPS; GMP synthase (glutamine-hydrolysing)
Enzymes [BR:ko01000]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.2 GMP synthase (glutamine-hydrolysing)
K01951 guaA, GMPS; GMP synthase (glutamine-hydrolysing)
Peptidases and inhibitors [BR:ko01002]
Cysteine peptidases
Family C26: gamma-glutamyl hydrolase family
K01951 guaA, GMPS; GMP synthase (glutamine-hydrolysing)
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Other DBs |
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Genes |
» show all
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Reference |
|
Authors |
Hirst M, Haliday E, Nakamura J, Lou L |
Title |
Human GMP synthetase. Protein purification, cloning, and functional expression of cDNA. |
Journal |
J Biol Chem 269:23830-7 (1994) |
Sequence |
|
Reference |
|
Authors |
Zalkin H, Argos P, Narayana SV, Tiedeman AA, Smith JM |
Title |
Identification of a trpG-related glutamine amide transfer domain in Escherichia coli GMP synthetase. |
Journal |
J Biol Chem 260:3350-4 (1985) |
Sequence |
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LinkDB |
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