KEGG REACTION: R01859

REACTION: R01859

Entry

R01859                      Reaction

Name

propanoyl-CoA:carbon-dioxide ligase (ADP-forming)

Definition

ATP + Propanoyl-CoA + HCO3- <=> ADP + Orthophosphate + (S)-Methylmalonyl-CoA

Equation

C00002 + C00100 + C00288 <=> C00008 + C00009 + C00683

Comment

possibly two-step reaction (similar to R00742 or R04385+R04386)

Reaction class

RC00002

C00002_C00008

RC00097

C00100_C00683

RC00609

C00288_C00683

Enzyme

6.4.1.3

Pathway

rn00280

Valine, leucine and isoleucine degradation

rn00630

Glyoxylate and dicarboxylate metabolism

rn00640

Propanoate metabolism

rn00720

Other carbon fixation pathways

rn01100

Metabolic pathways

rn01110

Biosynthesis of secondary metabolites

rn01120

Microbial metabolism in diverse environments

rn01200

Carbon metabolism

Module

M00373

Ethylmalonyl pathway

M00375

Hydroxypropionate-hydroxybutylate cycle

M00376

3-Hydroxypropionate bi-cycle

M00741

Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA

Brite

Enzymatic reactions [BR:br08201]
6. Ligase reactions
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.3
     R01859  ATP + Propanoyl-CoA + HCO3- <=> ADP + Orthophosphate + (S)-Methylmalonyl-CoA
Overall reaction [br08210.html]
Carbon fixation
  R01859

Orthology

K01964

acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]

K01965

propionyl-CoA carboxylase alpha subunit [EC:6.4.1.3]

K01966

propionyl-CoA carboxylase beta subunit [EC:6.4.1.3 2.1.3.15]

K11263

acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]

K15036

acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15]

K15037