KEGG   ORTHOLOGY: K18472
Entry
K18472                      KO                                     
Symbol
accD6
Name
acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
Pathway
map00061  Fatty acid biosynthesis
map00074  Mycolic acid biosynthesis
map00280  Valine, leucine and isoleucine degradation
map00620  Pyruvate metabolism
map00630  Glyoxylate and dicarboxylate metabolism
map00640  Propanoate metabolism
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map01212  Fatty acid metabolism
Module
M00082  Fatty acid biosynthesis, initiation
M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA
M00885  Meromycolic acid biosynthesis, initiation and elongation FAS II (KasA)
M00886  Meromycolic acid biosynthesis, initiation and elongation FAS II (KasA and KasB)
Reaction
R00742  acetyl-CoA:carbon-dioxide ligase (ADP-forming)
R01859  propanoyl-CoA:carbon-dioxide ligase (ADP-forming)
R04386  carboxybiotin-carboxyl-carrier-protein:acetyl-CoA carboxytransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    K18472  accD6; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit
   00630 Glyoxylate and dicarboxylate metabolism
    K18472  accD6; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit
   00640 Propanoate metabolism
    K18472  accD6; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    K18472  accD6; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit
   00074 Mycolic acid biosynthesis
    K18472  accD6; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    K18472  accD6; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.15  acetyl-CoA carboxytransferase
     K18472  accD6; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit
 6. Ligases
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     K18472  accD6; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit
    6.4.1.3  propionyl-CoA carboxylase
     K18472  accD6; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit
Other DBs
COG: COG4799
GO: 0003989 0004658
Genes
MTU: Rv2247(accD6)
MTV: RVBD_2247
MTC: MT2307(pccB-2)
MRA: MRA_2267(accD6)
MTF: TBFG_12276
MTB: TBMG_01733
MTK: TBSG_01743
MTZ: TBXG_001715
MTG: MRGA327_13875
MTI: MRGA423_13990
MTUR: CFBS_2380(accD6)
MTO: MTCTRI2_2283(accD6)
MTD: UDA_2247(accD6)
MTN: ERDMAN_2472(accD6)
MTUL: TBHG_02199
MTUT: HKBT1_2371(accD6)
MTUU: HKBT2_2373(accD6)
MTQ: HKBS1_2377(accD6)
MBO: BQ2027_MB2271(accD6)
MBB: BCG_2264(accD6)
MBT: JTY_2258(accD6)
MBM: BCGMEX_2252(accD6)
MBX: BCGT_2070
MAF: MAF_22580(accD6)
MMIC: RN08_2495
MCE: MCAN_22691(accD6)
MCQ: BN44_50190(accD)
MCV: BN43_31490(accD)
MCX: BN42_40171(accD)
MCZ: BN45_50579(accD)
MORY: MO_002356
MLE: ML1657
MLB: MLBr01657
MPA: MAP_2000(accD6)
MAO: MAP4_1825
MAVI: RC58_09120
MAVU: RE97_09125
MAV: MAV_2190
MIT: OCO_21770
MIA: OCU_21950
MID: MIP_03075
MYO: OEM_19660
MIR: OCQ_20870
MLP: MLM_1919
MMAN: MMAN_18040(accD6)
MSER: MTY59_37840(accD6)
MUL: MUL_1302(accD6)
MMI: MMAR_3340(accD6)
MMAE: MMARE11_32410(accD6)
MLI: MULP_03601(accD6)
MPSE: MPSD_34170(accD6)
MSHO: MSHO_47520(accD6)
MMC: Mmcs_3368
MKM: Mkms_3430
MJL: Mjls_3379
MMM: W7S_10235
MHAD: B586_09885
MSHG: MSG_03172(accD6)
MFJ: MFLOJ_00440(accD6)
MSTO: MSTO_01100(accD6)
MSIM: MSIM_45140(accD6)
MSAK: MSAS_12220(accD6)
MXE: MYXE_20710(accD6)
MNV: MNVI_45170(accD6)
MNM: MNVM_02390(accD6)
MCOO: MCOO_12840(accD6)
MBAI: MB901379_03012(accD5_2)
MSEO: MSEO_19590(accD6)
MHEK: JMUB5695_02080(accD6)
MLJ: MLAC_22610(accD6)
MBRD: MBRA_35600(accD6)
MSHJ: MSHI_10150(accD6)
MLM: MLPF_0932(accD6)
MKY: IWGMT90018_24100(accD6)
MSG: MSMEI_4229(accD6)
MVA: Mvan_3758
MGI: Mflv_2775
MPHL: MPHLCCUG_03394(accD6)
MVQ: MYVA_3580
MTHN: 4412656_01784(accD6)
MHAS: MHAS_01447(accD6)
MAUU: NCTC10437_03515(accD5_2)
MMAG: MMAD_35150(accD6)
MMOR: MMOR_29420
MFX: MFAL_13650(accD6)
MAIC: MAIC_34230(accD6)
MALV: MALV_02260
MARZ: MARA_61330
MGAD: MGAD_02930
MHEV: MHEL_60270(accD6)
MSAR: MSAR_35150(accD6)
MANY: MANY_19090(accD6)
MAUB: MAUB_50700
MPOF: MPOR_39310
MPHU: MPHO_18710
MBOK: MBOE_35980
MSEI: MSEDJ_47260(accD6)
MFLV: NCTC10271_01897(accD5_2)
MCEE: MCEL_03170(accD6)
MKR: MKOR_04690(accD6)
MAB: MAB_1876c
MABB: MASS_1863
MCHE: BB28_09680
MSTE: MSTE_01794
MSAL: DSM43276_01632(accD6_1) DSM43276_02531(accD6_2)
MJD: JDM601_1648(accD6)
MTER: 4434518_01561(accD6)
MMIN: MMIN_32480(accD6)
MHIB: MHIB_10820(accD6)
ASD: AS9A_1222
NFA: NFA_16180
NFR: ERS450000_02542(accD5_2)
NCY: NOCYR_1673(pccB1)
NAD: NCTC11293_02579(accD5_4)
RHA: RHA1_ro01202(pccB1)
RER: RER_36750
REY: O5Y_16900
ROP: ROP_09250(pccB)
RHB: NY08_583
RHU: A3Q40_01109(accD6)
RRT: 4535765_03065(accD5_3)
RCR: NCTC10994_04196(accD5_4)
RHOJ: JVH1_31350
RFA: A3L23_03832(accD6)
RHS: A3Q41_04410(accD6)
REQ: REQ_28980(accd6)
GBR: Gbro_3124
GPO: GPOL_c28880(accD6)
GOR: KTR9_3117
GRU: GCWB2_16230(accD4)
GOM: D7316_00149(accD6)
SCT: SCAT_p0298(accD)
LMOI: VV02_13285
DCO: SAMEA4475696_1549(accD5_2)
NCA: Noca_1986
NDK: I601_3723(accD6)
NAQU: ENKNEFLB_02681(accD6)
PSIM: KR76_18745
KFL: Kfla_2564
TCU: Tcur_1637
SRO: Sros_7058
NCX: Nocox_25660(accD3) Nocox_31040(accD6)
TBI: Tbis_2373
FAL: FRAAL3857 FRAAL5672(pccB)
ACE: Acel_0874
NML: Namu_2037
GOB: Gobs_3514
BSD: BLASA_1970(pccB)
MMAR: MODMU_1841(pccB)
AMYY: YIM_18740(accD2) YIM_40295(accD4)
AMYZ: HUW46_03419(accD6)
PDX: Psed_0517
PSEA: WY02_00215
KAL: KALB_1214
ALO: CRK55634
SAQ: Sare_3624
ASE: ACPL_1521
ACTS: ACWT_1400
ACTE: ACTI_34080
PFLA: Pflav_007820(accD6_1) Pflav_054690 Pflav_057170(accD6_2)
CAI: Caci_6813
SNA: Snas_4812
 » show all
Reference
  Authors
Daniel J, Oh TJ, Lee CM, Kolattukudy PE
  Title
AccD6, a member of the Fas II locus, is a functional carboxyltransferase subunit of the acyl-coenzyme A carboxylase in Mycobacterium tuberculosis.
  Journal
J Bacteriol 189:911-7 (2007)
DOI:10.1128/JB.01019-06
  Sequence
[mtu:Rv2247]
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