REACTION: R02401
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Entry
R02401 Reaction
Name
glutarate-semialdehyde:NAD+ oxidoreductase
Definition
5-Oxopentanoate + NAD+ + H2O <=> Glutarate + NADH + H+
Equation
C03273
+
C00003
+
C00001
<=>
C00489
+
C00004
+
C00080
Reaction class
RC00001
C00003_C00004
RC00080
C00489_C03273
Enzyme
1.2.1.20
Pathway
rn00310
Lysine degradation
rn01100
Metabolic pathways
rn01120
Microbial metabolism in diverse environments
Module
M00956
Lysine degradation, bacteria, L-lysine => succinate
M00957
Lysine degradation, bacteria, L-lysine => glutarate => succinate/acetyl-CoA
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.20
R02401 5-Oxopentanoate + NAD+ + H2O <=> Glutarate + NADH + H+
BRITE hierarchy
Orthology
K00135
succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:
1.2.1.16
1.2.1.79
1.2.1.20
]
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