KEGG REACTION: R03145

REACTION: R03145

Entry

R03145                      Reaction

Name

pyruvate:ubiquinone oxidoreductase

Definition

Pyruvate + Ubiquinone + H2O <=> Acetate + Ubiquinol + CO2

Equation

C00022 + C00399 + C00001 <=> C00033 + C00390 + C00011

Comment

previously called pyruvate:ferricytochrome-b1 oxidoreductase (ec 1.2.2.2)
ubiquinol is re-oxidized by ferricytochrome in respiratory chain

Reaction class

RC00061

C00390_C00399

RC00860

C00022_C00033

Enzyme

1.2.5.1

Pathway

rn00620

Pyruvate metabolism

rn01100

Metabolic pathways

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.5  With a quinone or similar compound as acceptor
    1.2.5.1
     R03145  Pyruvate + Ubiquinone + H2O <=> Acetate + Ubiquinol + CO2

Orthology

K00156

pyruvate dehydrogenase (quinone) [EC:1.2.5.1]

LinkDB

RCLASS: RC00860

Entry

RC00860                     RClass

Definition

C5a-C6a:C6a+*-*+O6a:C1a+O5a-C1a+O6a

Reactant pair