REACTION: R03325
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Entry
R03325 Reaction
Name
17alpha,20alpha-dihydroxypregn-4-en-3-one:NADP+ 20-oxidoreductase
Definition
17alpha,20alpha-Dihydroxypregn-4-en-3-one + NADP+ <=> 17alpha-Hydroxyprogesterone + NADPH + H+
Equation
C04518
+
C00006
<=>
C01176
+
C00005
+
C00080
Comment
NAD+ (see
R03324
)
Reaction class
RC00001
C00005_C00006
RC00228
C01176_C04518
Enzyme
1.1.1.149
Pathway
rn00140
Steroid hormone biosynthesis
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.149
R03325 17alpha,20alpha-Dihydroxypregn-4-en-3-one + NADP+ <=> 17alpha-Hydroxyprogesterone + NADPH + H+
BRITE hierarchy
Orthology
K00212
20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:
1.1.1.149
1.1.1.357
1.3.1.20
]
K05295
20alpha-hydroxysteroid dehydrogenase [EC:
1.1.1.149
]
Other DBs
RHEA:
15860
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