KEGG REACTION: R03332

REACTION: R03332

Entry

R03332                      Reaction

Name

1-phosphatidyl-D-myo-inositol inositolphosphohydrolase

Definition

1-Phosphatidyl-D-myo-inositol + H2O <=> Inositol 1-phosphate + 1,2-Diacyl-sn-glycerol

Equation

C01194 + C00001 <=> C01177 + C00641

Reaction class

RC00017

C00641_C01194

RC00425

C01177_C01194

Enzyme

3.1.4.3 3.1.4.11 4.6.1.13

Pathway

rn00562

Inositol phosphate metabolism

rn01100

Metabolic pathways

Brite

Enzymatic reactions [BR:br08201]
3. Hydrolase reactions
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.3
     R03332  1-Phosphatidyl-D-myo-inositol + H2O <=> Inositol 1-phosphate + 1,2-Diacyl-sn-glycerol
    3.1.4.11
     R03332  1-Phosphatidyl-D-myo-inositol + H2O <=> Inositol 1-phosphate + 1,2-Diacyl-sn-glycerol
4. Lyase reactions
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.13
     R03332  1-Phosphatidyl-D-myo-inositol + H2O <=> Inositol 1-phosphate + 1,2-Diacyl-sn-glycerol

Orthology

K01114

phospholipase C [EC:3.1.4.3]

K01116

phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]

K01771

1-phosphatidylinositol phosphodiesterase [EC:4.6.1.13]

K05857

phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]

K05858

phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]

K05859