KEGG   REACTION: R03896
Entry
R03896                      Reaction                               
Name
(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)
Definition
(R)-2-Methylmalate <=> 2-Methylmaleate + H2O
Equation
C02612 <=> C02226 + C00001
Reaction class
RC00976  C02226_C02612
Enzyme
4.2.1.35
Pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn00660  C5-Branched dibasic acid metabolism
rn01100  Metabolic pathways
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00535  Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.35
     R03896  (R)-2-Methylmalate <=> 2-Methylmaleate + H2O
Orthology
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
K01704  3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
Other DBs
RHEA: 22335
LinkDB

KEGG   RCLASS: RC00976
Entry
RC00976                     RClass                                 
Definition
C1b-C2b:*-*:C1d+C6a-C2c+C6a
C1d-C2c:O1a-*:C1a+C1b+C6a-C1a+C2b+C6a
Reactant pair
C01732_C02614    C02226_C02612
Related class
Reaction
R03693 R03896
Enzyme
4.2.1.34        4.2.1.35
Pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn00660  C5-Branched dibasic acid metabolism
rn01100  Metabolic pathways
rn01210  2-Oxocarboxylic acid metabolism
RModule
RM001  2-Oxocarboxylic acid chain extension by tricarboxylic acid pathway
Orthology
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
K01704  3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]

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