| Entry |
|
| Symbol |
leuD, IPMI-S
|
| Name |
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC: 4.2.1.33 4.2.1.35]
|
| Pathway |
| map00290 | Valine, leucine and isoleucine biosynthesis |
| map00660 | C5-Branched dibasic acid metabolism |
| map01110 | Biosynthesis of secondary metabolites |
| map01210 | 2-Oxocarboxylic acid metabolism |
|
| Module |
| M00432 | Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate |
| M00535 | Isoleucine biosynthesis, pyruvate => 2-oxobutanoate |
|
| Reaction |
| R03896 | (R)-2-methylmalate hydro-lyase (2-methylmaleate-forming) |
| R03898 | 2-methylmaleate hydratase |
| R03968 | 2-isopropylmalate hydro-lyase |
| R04001 | 3-isopropylmalate hydro-lyase |
| R10170 | (2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming) |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
K01704 leuD, IPMI-S; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
K01704 leuD, IPMI-S; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit
Enzymes [BR:ko01000]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
K01704 leuD, IPMI-S; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit
4.2.1.35 (R)-2-methylmalate dehydratase
K01704 leuD, IPMI-S; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit
Enzymes of 2-oxocarboxylic acid metabolism [br01601.html]
2-Oxoacid chain elongation
K01704
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| Other DBs |
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| Genes |
» show all
|
| Reference |
|
| Authors |
Drevland RM, Waheed A, Graham DE |
| Title |
Enzymology and evolution of the pyruvate pathway to 2-oxobutyrate in Methanocaldococcus jannaschii. |
| Journal |
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| Sequence |
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| LinkDB |
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