KEGG   REACTION: R04035
Entry
R04035                      Reaction                               
Name
phosphoribosyl-ATP pyrophosphohydrolase
Definition
1-(5-Phospho-D-ribosyl)-ATP + H2O <=> Phosphoribosyl-AMP + Diphosphate
Equation
C02739 + C00001 <=> C02741 + C00013
Reaction class
RC00002  C02739_C02741
Enzyme
3.6.1.31
Pathway
rn00340  Histidine metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01230  Biosynthesis of amino acids
Module
M00026  Histidine biosynthesis, PRPP => histidine
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.31
     R04035  1-(5-Phospho-D-ribosyl)-ATP + H2O <=> Phosphoribosyl-AMP + Diphosphate
Orthology
K01523  phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
K11755  phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31]
K14152  phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]
Other DBs
RHEA: 22831
LinkDB

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